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Leone, Gustavo
One or more keywords matched the following items that are connected to Leone, Gustavo
Item TypeName
Concept Proto-Oncogene Protein c-ets-1
Concept Protein-Tyrosine Kinases
Concept Bone Morphogenetic Protein 3
Concept Protein Binding
Concept Protein Folding
Concept Protein Processing, Post-Translational
Concept Tumor Suppressor Protein p53
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Retinoblastoma Protein
Concept Protein Kinase Inhibitors
Concept Protein Phosphatase 2
Concept Mitogen-Activated Protein Kinase 1
Concept Protein Biosynthesis
Concept Retinoblastoma-Like Protein p130
Concept Cyclic AMP-Dependent Protein Kinases
Concept Protein Kinases
Concept Protein Precursors
Concept Protein Interaction Domains and Motifs
Concept Proto-Oncogene Protein c-ets-2
Concept AMP-Activated Protein Kinases
Concept Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
Concept Mitogen-Activated Protein Kinase 3
Concept Early Growth Response Protein 1
Concept Protein Structure, Secondary
Concept Inhibitor of Differentiation Protein 2
Concept Ubiquitin-Protein Ligases
Concept Protein Structure, Tertiary
Concept Oncogene Protein v-akt
Concept Retinoblastoma-Binding Protein 1
Concept SKP Cullin F-Box Protein Ligases
Concept Myeloid-Lymphoid Leukemia Protein
Concept Protein Stability
Concept Protein Kinase C-alpha
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept bcl-X Protein
Concept Protein Sorting Signals
Concept Protein Isoforms
Concept Protein Conformation
Academic Article Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
Academic Article Molecular cloning and expression of equine calcitonin, calcitonin gene-related peptide-I, and calcitonin gene-related peptide-II.
Academic Article Extra-embryonic function of Rb is essential for embryonic development and viability.
Academic Article Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice.
Academic Article Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.
Academic Article Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells.
Academic Article Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.
Academic Article Aberrant regulation of survivin by the RB/E2F family of proteins.
Academic Article Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice.
Academic Article Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.
Academic Article Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
Academic Article E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
Academic Article Rb is critical in a mammalian tissue stem cell population.
Academic Article Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
Academic Article Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.
Academic Article Detection and visualization of surface-pockets to enable phenotyping studies.
Academic Article Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.
Academic Article E2f3a and E2f3b contribute to the control of cell proliferation and mouse development.
Academic Article Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
Academic Article Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Academic Article Emerging roles of E2Fs in cancer: an exit from cell cycle control.
Academic Article E2F3 is a mediator of DNA damage-induced apoptosis.
Academic Article Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.
Academic Article Division and apoptosis of E2f-deficient retinal progenitors.
Academic Article E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Academic Article An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
Academic Article Allele-specific tumor spectrum in pten knockin mice.
Academic Article Cell proliferation in the absence of E2F1-3.
Academic Article S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.
Academic Article Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.
Academic Article Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Academic Article Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Academic Article Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Academic Article The Spectrum of E2F in Liver Disease--Mediated Regulation in Biology and Cancer.
Academic Article FGFR and PTEN signaling interact during lens development to regulate cell survival.
Academic Article Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.
Academic Article E2f8 mediates tumor suppression in postnatal liver development.
Academic Article Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Academic Article Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
Academic Article Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Academic Article Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Academic Article The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.
Academic Article Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps.
Academic Article A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer.
Academic Article CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Academic Article Stromal PTEN determines mammary epithelial response to radiotherapy.
Academic Article hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
Academic Article Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Academic Article Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Academic Article Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Academic Article The E2F1-3 transcription factors are essential for cellular proliferation.
Academic Article E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
Academic Article Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
Academic Article The reovirus cell attachment protein possesses two independently active trimerization domains: basis of dominant negative effects.
Academic Article RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Academic Article annoPeak: a web application to annotate and visualize peaks from ChIP-seq/ChIP-exo-seq.
Academic Article DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2.
Academic Article Analysis of Cdc6 function in the assembly of mammalian prereplication complexes.
Academic Article Rb regulates proliferation and rod photoreceptor development in the mouse retina.
Academic Article Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages.
Academic Article Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.
Academic Article The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway.
Academic Article QChIPat: a quantitative method to identify distinct binding patterns for two biological ChIP-seq samples in different experimental conditions.
Academic Article A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Academic Article Crosstalk between PKCa and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium.
Academic Article The broken cycle: E2F dysfunction in?cancer.
Academic Article Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs.
Academic Article Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Academic Article Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimer.
Academic Article Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function.
Academic Article The N-terminal heptad repeat region of reovirus cell attachment protein sigma 1 is responsible for sigma 1 oligomer stability and possesses intrinsic oligomerization function.
Academic Article The incorporation of reovirus cell attachment protein sigma 1 into virions requires the N-terminal hydrophobic tail and the adjacent heptad repeat region.
Academic Article Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein.
Academic Article The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function.
Academic Article E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
Academic Article Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment.
Academic Article Reovirus protein sigma 1: from cell attachment to protein oligomerization and folding mechanisms.
Academic Article C-terminal trimerization, but not N-terminal trimerization, of the reovirus cell attachment protein Is a posttranslational and Hsp70/ATP-dependent process.
Academic Article Co-translational trimerization of the reovirus cell attachment protein.
Academic Article The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.
Academic Article Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.
Academic Article Distinct roles for E2F proteins in cell growth control and apoptosis.
Academic Article Functional analysis of E2F transcription factor.
Academic Article Role of the Rb/E2F pathway in cell growth control.
Academic Article E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
Academic Article Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells.
Academic Article Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth.
Academic Article Ras enhances Myc protein stability.
Academic Article Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase.
Academic Article Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
Academic Article High cyclin-dependent kinase inhibitors in Bcl-2 and Bcl-xL-expressing CD34+-proliferating haematopoietic progenitors.
Academic Article Expression of p15(INK4B) in hematopoietic progenitors.
Academic Article Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway.
Academic Article Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death.
Academic Article T-cell apoptosis induced by granulocyte colony-stimulating factor is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors.
Academic Article Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.
Academic Article Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein.
Academic Article BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
Academic Article Cyclin D-CDK4/6 functions in cancer.
Academic Article Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia.
Concept Protein Interaction Maps
Concept Transcription Factor 7-Like 2 Protein
Concept Zinc Finger Protein GLI1
Concept Jagged-1 Protein
Concept Tumor Protein p73
Concept Protein Domains
Concept S100 Calcium Binding Protein A7
Concept Zinc Finger Protein Gli2
Academic Article Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
Academic Article RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Academic Article Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Academic Article RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Academic Article The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state.
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  • Protein C